Agammaglobulinemia - Lack of antibodies in the blood.

 Amyloidosis - Disease characterized by the deposition of amyloid in the connective tissues, inhibiting normal organ functioning.

Disease characterized by the deposition of amyloid in the connective tissues, inhibiting normal organ functioning.

 Anemia - A condition in which there is a deficiency of red blood cells or of haemoglobin in the blood, resulting in pallor and weariness.

A condition in which there is a deficiency of red blood cells or of haemoglobin in the blood, resulting in pallor and weariness.

 Anemia, Aplastic - Also called ANEMIA OF BONE-MARROW FAILURE, disease in which bone marrow fails to produce an adequate number of blood cells. Symptoms of chronic aplastic anemia include weakness and fatigue in the early stages, followed by shortness of breath, headache, fever, and pounding heart. There is usually a waxy pallor, and hemorrhages occur in the mucous membranes, skin, and other organs. 

Also called ANEMIA OF BONE-MARROW FAILURE, disease in which bone marrow fails to produce an adequate number of blood cells. Symptoms of chronic aplastic anemia include weakness and fatigue in the early stages, followed by shortness of breath, headache, fever, and pounding heart. There is usually a waxy pallor, and hemorrhages occur in the mucous membranes, skin, and other organs. 

 Anemia, Hemolytic - Destruction of red cells at a rate substantially greater than normal, if not compensated for by accelerated red cell production, causes a type of anemia called hemolytic.

Destruction of red cells at a rate substantially greater than normal, if not compensated for by accelerated red cell production, causes a type of anemia called hemolytic.

 Anemia, Hemolytic, Congenital Nonspherocytic

 Anemia, Megaloblastic - It develops as the result of dietary deficiency of, faulty absorption of, or increased demands for vitamin B₁₂and/or folic acid.

It develops as the result of dietary deficiency of, faulty absorption of, or increased demands for vitamin B₁₂and/or folic acid.

 Anemia, Pernicious - It is one of many types of anemia, a disease marked by a reduction in red blood cells or in the oxygen-carrying substance hemoglobin found in those cells.Symptoms and signs include weakness; waxy pallor; smooth, shiny tongue; gastrointestinal disturbances; and neurologic problems.

It is one of many types of anemia, a disease marked by a reduction in red blood cells or in the oxygen-carrying substance hemoglobin found in those cells.Symptoms and signs include weakness; waxy pallor; smooth, shiny tongue; gastrointestinal disturbances; and neurologic problems.

 Anemia, Sickle Cell - Serious hereditary disease that affects the blood. Chief symptoms are chronic anemia (caused by excessive destruction of red blood cells); shortness of breath; fever; and episodic crises that are characterized by severe pain in the abdomen, bones, or muscles.

Serious hereditary disease that affects the blood. Chief symptoms are chronic anemia (caused by excessive destruction of red blood cells); shortness of breath; fever; and episodic crises that are characterized by severe pain in the abdomen, bones, or muscles.

 Bernard-Soulier Syndrome - It is an inherited disorder associated with a pronounced bleeding tendency, is due to a deficiency of glycoprotein Ib on the platelet membrane.

It is an inherited disorder associated with a pronounced bleeding tendency, is due to a deficiency of glycoprotein Ib on the platelet membrane.

 Blood Coagulation Disorders - Coagulation disorders include a number of disorders that are related to defects in the clotting of blood. Spontaneous bleeding into joints, giving rise to severe chronic arthritis, is a common problem among patients with severe hemophilia; in addition, there is bleeding into the brain and the abdominal cavity, as well as marked bruising.

Coagulation disorders include a number of disorders that are related to defects in the clotting of blood. Spontaneous bleeding into joints, giving rise to severe chronic arthritis, is a common problem among patients with severe hemophilia; in addition, there is bleeding into the brain and the abdominal cavity, as well as marked bruising.

 Blood Platelet Disorders - Abnormal bleeding follows a pattern defined by the underlying defect. Platelet abnormalities are associated with spontaneous bleeding from the membranes of the nose, mouth, and gastrointestinal and urogenital tracts.

Abnormal bleeding follows a pattern defined by the underlying defect. Platelet abnormalities are associated with spontaneous bleeding from the membranes of the nose, mouth, and gastrointestinal and urogenital tracts.

 Christmas Disease ( --> Hemophilia B) - Also spelled Haemophilia, hereditary bleeding disorder caused by a deficiency of a substance necessary for blood clotting.

Also spelled Haemophilia, hereditary bleeding disorder caused by a deficiency of a substance necessary for blood clotting.

 Cryoglobulinemia - It is usually symptomatic of an underlying disease, such as multiple myeloma or chronic lymphocytic leukemia; it may disappear, sometimes permanently, after the primary disease abates.

It is usually symptomatic of an underlying disease, such as multiple myeloma or chronic lymphocytic leukemia; it may disappear, sometimes permanently, after the primary disease abates.

 Disseminated Intravascular Coagulation - It is an acquired disorder in which the blood coagulation system is activated inappropriately, and the normal regulatory mechanisms are overwhelmed.

It is an acquired disorder in which the blood coagulation system is activated inappropriately, and the normal regulatory mechanisms are overwhelmed.

 Eosinophilia - It is an increase in the number of eosinophilic leukocytes, is encountered in many allergic reactions and parasitic infections. It is especially characteristic of infestation by trichina larvae, which are ingested when infected and poorly cooked pork or pork products are eaten.

It is an increase in the number of eosinophilic leukocytes, is encountered in many allergic reactions and parasitic infections. It is especially characteristic of infestation by trichina larvae, which are ingested when infected and poorly cooked pork or pork products are eaten.

 Erythroblastosis, Fetal - It is a disease in which the red blood cells of the fetus are destroyed because of an incompatibility between the infant's blood and that of the mother.

It is a disease in which the red blood cells of the fetus are destroyed because of an incompatibility between the infant's blood and that of the mother.

 Evans Syndrome

 Factor V Leiden ( --> Blood Coagulation Disorders)

 Factor X Deficiency

 Factor XI Deficiency

 Fanconi's Anemia

 Favism - A hereditary disorder involving an allergic-like reaction to the broad, or fava, bean (Vicia faba). Susceptible persons may develop a blood disorder (hemolytic anemia).

A hereditary disorder involving an allergic-like reaction to the broad, or fava, bean (Vicia faba). Susceptible persons may develop a blood disorder (hemolytic anemia).

 Giant Lymph Node Hyperplasia

 Hemoglobinopathies - Also spelled HAEMOGLOBINOPATHY, any of a group of disorders caused by the presence of abnormal hemoglobin in the red blood cells.

Also spelled HAEMOGLOBINOPATHY, any of a group of disorders caused by the presence of abnormal hemoglobin in the red blood cells.

 Hemolytic-Uremic Syndrome - (Hemic .. Diseases)

 Hemophilia A - It is caused by the absence of the coagulation protein factor VIII. Spontaneous bleeding into joints, there is bleeding into the brain and the abdominal cavity, as well as marked bruising. In general, the greater the deficiency in either factor VIII or factor IX, the more severe the manifestations of disease.

It is caused by the absence of the coagulation protein factor VIII. Spontaneous bleeding into joints, there is bleeding into the brain and the abdominal cavity, as well as marked bruising. In general, the greater the deficiency in either factor VIII or factor IX, the more severe the manifestations of disease.

 Hemophilia B - It is due to factor IX deficiency. Spontaneous bleeding into joints, there is bleeding into the brain and the abdominal cavity, as well as marked bruising. In general, the greater the deficiency in either factor VIII or factor IX, the more severe the manifestations of disease.

It is due to factor IX deficiency. Spontaneous bleeding into joints, there is bleeding into the brain and the abdominal cavity, as well as marked bruising. In general, the greater the deficiency in either factor VIII or factor IX, the more severe the manifestations of disease.

 Hemorrhagic Disease of Newborn - Vitamin K deficiency is associated with obstructive jaundice, in which the flow of bile into the bowel is interrupted. Vitamin K deficiency also occurs in the newborn infant as hemorrhagic disease of the newborn.

Vitamin K deficiency is associated with obstructive jaundice, in which the flow of bile into the bowel is interrupted. Vitamin K deficiency also occurs in the newborn infant as hemorrhagic disease of the newborn.

 Histiocytosis, Sinus

 Job's Syndrome

 Lymphangiomyomatosis

Lymphedema - An abnormal condition in which drainage of the lymphatic system is blocked, allowing fluid to build up in the tissues. The lymphedema in all these types usually involves both legs below the knees and begins as a painless swelling in the foot that moves up to the leg as it progresses. Although the swelling is initially painless, it may impair leg function in extreme cases and be cosmetically undesirable.

 Monoclonal Gammopathy ( --> Paraproteinemias)

 Myelodysplastic Syndromes

 Myelofibrosis

 Myeloproliferative Disorders

 Neutropenia

 Paraproteinemias

 Polycythemia Vera - The situation in which excess red blood cells occur without known cause is called erythremia, primary polycythemia, or polycythemia vera. Symptoms include headache, dizziness, difficulty in breathing, skin changes (e.g.,tendency to bruise), an enlarged spleen, and red discoloration of the face and sometimes the extremities.

The situation in which excess red blood cells occur without known cause is called erythremia, primary polycythemia, or polycythemia vera. Symptoms include headache, dizziness, difficulty in breathing, skin changes (e.g.,tendency to bruise), an enlarged spleen, and red discoloration of the face and sometimes the extremities.

 Purpura, Thrombocytopenic - A rash of purple spots on the skin caused by internal bleeding from small blood vessels.

A rash of purple spots on the skin caused by internal bleeding from small blood vessels.

 Rh Isoimmunization

 Sarcoidosis - Systemic disease of unknown cause that is characterized by the formation of granulation (scarlike) tissue. It often disappears spontaneously within two or three years but may progress to involve more than one organ. It is observed in the lungs, lymph nodes, eyes, salivary glands, muscles, liver, spleen, and the connective tissues of the nervous system.

Systemic disease of unknown cause that is characterized by the formation of granulation (scarlike) tissue. It often disappears spontaneously within two or three years but may progress to involve more than one organ. It is observed in the lungs, lymph nodes, eyes, salivary glands, muscles, liver, spleen, and the connective tissues of the nervous system.

 Sarcoidosis, Pulmonary

 Spherocytosis, Hereditary - The most frequent of the familial anemias, is inherited as an autosomal dominant (an inherited characteristic not related to sex). Symptoms may be present at birth or may not appear until old age; the disease is most often identified during childhood or adolescence. Removal of the spleen results in cure of anemia in nearly all cases; the defects in blood production remain but do not cause serious disability.

The most frequent of the familial anemias, is inherited as an autosomal dominant (an inherited characteristic not related to sex). Symptoms may be present at birth or may not appear until old age; the disease is most often identified during childhood or adolescence. Removal of the spleen results in cure of anemia in nearly all cases; the defects in blood production remain but do not cause serious disability.

 Splenic Diseases

 Stuart-Prower Deficiency ( --> Factor X Deficiency)

 Thalassemia - Also called COOLEY'S ANEMIA, MEDITERRANEAN ANEMIA, OR HEREDITARY LEPTOCYTOSIS, group of blood disorders characterized by a deficiency of hemoglobin, the blood protein that transports oxygen to the tissues. It is caused by genetically determined abnormalities in the synthesis of one or more of the polypeptide chains that make up the globin part of hemoglobin.

Also called COOLEY'S ANEMIA, MEDITERRANEAN ANEMIA, OR HEREDITARY LEPTOCYTOSIS, group of blood disorders characterized by a deficiency of hemoglobin, the blood protein that transports oxygen to the tissues. It is caused by genetically determined abnormalities in the synthesis of one or more of the polypeptide chains that make up the globin part of hemoglobin.

 Thrombasthenia - Also called THROMBOCYTASTHENIA, any of several blood disorders characterized by abnormal blood platelets, the dysfunction of these platelets results in prolonged bleeding time, defective clot formation, and a tendency to hemorrhage.

Also called THROMBOCYTASTHENIA, any of several blood disorders characterized by abnormal blood platelets, the dysfunction of these platelets results in prolonged bleeding time, defective clot formation, and a tendency to hemorrhage.

 Thrombocytopenia - Deficiency of platelets in the blood. This causes bleeding into the tissues, bruising, and slow blood clotting after injury.


Deficiency of platelets in the blood. This causes bleeding into the tissues, bruising, and slow blood clotting after injury.


 Triosephosphate Isomerase Deficiency ( --> Anemia, Hemolytic, Congenital Nonspherocytic)

 von Willebrand Disease - Also called PSEUDOHEMOPHILIA B, VASCULAR HEMOPHILIA, OR ANGIOHEMOPHILIA, inherited hemorrhagic disorder characterized by a prolonged bleeding time and a deficiency of antihemophilic factor (factor VIII), which is an important blood clotting agent.

Also called PSEUDOHEMOPHILIA B, VASCULAR HEMOPHILIA, OR ANGIOHEMOPHILIA, inherited hemorrhagic disorder characterized by a prolonged bleeding time and a deficiency of antihemophilic factor (factor VIII), which is an important blood clotting agent.

 Waldenstrom Macroglobulinemia

 Wiskott-Aldrich Syndrome